Our drug development program focuses on drug repurposing – testing existing drugs to see if they can also be beneficial for vitiligo patients. Historical examples of repurposing from global pharma provide a clear precedent for our own repurposing activities, suggesting that success is possible.
This is proving particularly fruitful in the search for new treatments for non-life threatening diseases such as vitiligo, which are often neglected by the research community.
The scientific rationale behind drug repurposing is supported by two core scientific concepts.
- A single drug often interacts with multiple targets
- Targets relevant to one disease or biological process are often involved in several biological processes.
We are currently in the first stage of the program, where we are focusing on off-label use of approved drugs already on the market and thus available to vitiligo patients immediately.
Such an approach would minimize a complex, multi-year and multi-million dollar study necessary at an early drug development stage. The most promising compounds and drugs will be tested in pre-clinical trials to evaluate their ability to slow or stop the vitiligo progression and induce repigmentation.
Such an approach would minimize a complex, multi-year and multi-million dollar study necessary at an early drug development stage. The most promising compounds and drugs will be tested in pre/clinical trials to evaluate their ability to slow or stop the vitiligo progression and induce regimentation.
Promising results from our drug re-purposing program were presented at the EADV Spring Symposium on May 24, 2013. These showed that Sodium Oxodihydroacridinylacetate, an active ingredient of NEOVIR produced by Pharmsyntez in Russia, is effective in stopping vitiligo progression. Read more here.
I support the petition to designate June 25 as Vitiligo World Day and save millions of people worldwide from social isolation and persecution.
What is coming?
NY Vitiligo Community Meeting in September
Our next meeting will be on Thursday, September 21st, at 7PM - 8:30PM on the 11th floor of NYU's Ambulatory Care Center at 240 East 38th Street, between 2nd and 3rd Av...21 September 2017 19:00, 11th floor of NYU's Ambulatory Car...
Vitiligo Advocacy Day at the US Capitol
Save-the-Date for the much anticipated Vitiligo Advocacy Day at the United States Capitol this fall. As many of you know, the Advocacy Committee of the Global Vitilig...04 October 2017 10:00, Washington, DC
Polypodium leucotomos as an adjunct treatment for vitiligo?
Extracts of the tropical fern Polypodium leucotomos appear to possess beneficial properties for the vitiligious skin. Polypodium leucotomos (also classified as Polypo...
Why there is no drug for vitiligo yet?
Despite the dearth of medications available to treat psoriasis - a disease with similar prevalence numbers and impact on quality of life - vitiligo has no known cure o...
Is there a traditional medicine to treat vitiligo?
During the last decades, new methods of therapeutic research, ethno-botany and ethno-pharmacology and even archeo-pharmacology (PubMed), have been used extensively to ...
I have a new job - should I tell colleagues about my vitiligo?
If you are starting a new job and you are concerned about stares and questions about your skin, try a proactive approach. When the time is right and you are feeling co...