Our drug development program focuses on drug repurposing – testing existing drugs to see if they can also be beneficial for vitiligo patients. Historical examples of repurposing from global pharma provide a clear precedent for our own repurposing activities, suggesting that success is possible.
This is proving particularly fruitful in the search for new treatments for non-life threatening diseases such as vitiligo, which are often neglected by the research community.
The scientific rationale behind drug repurposing is supported by two core scientific concepts.
- A single drug often interacts with multiple targets
- Targets relevant to one disease or biological process are often involved in several biological processes.
We are currently in the first stage of the program, where we are focusing on off-label use of approved drugs already on the market and thus available to vitiligo patients immediately.
Such an approach would minimize a complex, multi-year and multi-million dollar study necessary at an early drug development stage. The most promising compounds and drugs will be tested in pre-clinical trials to evaluate their ability to slow or stop the vitiligo progression and induce repigmentation.
Such an approach would minimize a complex, multi-year and multi-million dollar study necessary at an early drug development stage. The most promising compounds and drugs will be tested in pre/clinical trials to evaluate their ability to slow or stop the vitiligo progression and induce regimentation.
Promising results from our drug re-purposing program were presented at the EADV Spring Symposium on May 24, 2013. These showed that Sodium Oxodihydroacridinylacetate, an active ingredient of NEOVIR produced by Pharmsyntez in Russia, is effective in stopping vitiligo progression. Read more here.
I support the petition to designate June 25 as Vitiligo World Day and save millions of people worldwide from social isolation and persecution.
What is coming?
New York Vitiligo Community Meeting
Our next meeting will be after the World Vitiligo Day conference in Detroit on Thursday, July 20th, 2017, at 7PM - 8:30PM on the 11th floor of NYU's Ambulatory Care Ce...20 July 2017 19:00, 240 East 38th Street, New York, NY
Master Class On Vitiligo In Pediatric Age
will be held alongside “International Forum on Paediatric Dermatology”, which will take place in Rome (Italy), on October 5-7, 2017. This is an exciting opportunity t...06 October 2017 09:00, P.zza Giovanni Randaccio, 1 - Rome...
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