Our drug development program focuses on drug repurposing – testing existing drugs to see if they can also be beneficial for vitiligo patients. Historical examples of repurposing from global pharma provide a clear precedent for our own repurposing activities, suggesting that success is possible.
This is proving particularly fruitful in the search for new treatments for non-life threatening diseases such as vitiligo, which are often neglected by the research community.
The scientific rationale behind drug repurposing is supported by two core scientific concepts.
- A single drug often interacts with multiple targets
- Targets relevant to one disease or biological process are often involved in several biological processes.
We are currently in the first stage of the program, where we are focusing on off-label use of approved drugs already on the market and thus available to vitiligo patients immediately.
Such an approach would minimize a complex, multi-year and multi-million dollar study necessary at an early drug development stage. The most promising compounds and drugs will be tested in pre-clinical trials to evaluate their ability to slow or stop the vitiligo progression and induce repigmentation.
Such an approach would minimize a complex, multi-year and multi-million dollar study necessary at an early drug development stage. The most promising compounds and drugs will be tested in pre/clinical trials to evaluate their ability to slow or stop the vitiligo progression and induce regimentation.
Promising results from our drug re-purposing program were presented at the EADV Spring Symposium on May 24, 2013. These showed that Sodium Oxodihydroacridinylacetate, an active ingredient of NEOVIR produced by Pharmsyntez in Russia, is effective in stopping vitiligo progression. Read more here.
I support the petition to designate June 25 as Vitiligo World Day and save millions of people worldwide from social isolation and persecution.
What is coming?
VITFriends Fundraising and Awareness Concert in Boston
Featuring: M.C. - Mary-dith Tuitt Jazz vocalist - Katani Summer Steel drum instrumentalist - Justin Petty Vocalist - Emily Orji and Dr. Victor Huan...30 April 2017 14:30, Salvation Army Kroc Center, 650 Du...
Vitiligo Walk-A-Thon in Fort Dallas
The annual Vitiligo Walkathon is organized by Dallas Fort Worth Vitiligo Support Group on May 20, 2017. This is an event held to raise awareness about vitiligo in the...20 May 2017 09:00, Dallas, Texas
Are there any famous people with vitiligo?
Many celebrities have dealt with vitiligo while remaining in the public eye, maintaining a positive outlook, and having a successful career. Here are a few courageous ...
Isn't it just a cosmetic disorder?
Like it or not, we live in a society where appearance matters. It should come as no surprise that vitiligo impacts on the psychological well-being and quality of life ...
I have a new job - should I tell colleagues about my vitiligo?
If you are starting a new job and you are concerned about stares and questions about your skin, try a proactive approach. When the time is right and you are feeling co...
What causes vitiligo?
The precise cause of vitiligo is not well understood. The white areas appear due to loss of the pigment (melanin) that gives skin its color and protects it from the su...