XVII Master Class on Vitiligo in Manaus, Brazil on June 2016

Master Class Vitiligo Manaus 2016 1Over 100 participants of XVII Master Class on Vitiligo in Manaus explored genetic risk factors in vitiligo, treatment approach to patients of pediatric and adult age, a variety of therapeutic options for vitiligo, including 'traditional medicines' of Amazon tribes. Presentations on melasma, actinic dermatoses and challenging clinical cases enhanced the intensive program. Participants have also received the reference data on the active ingredients, side effects, potential interactions between herbal supplements and conventional medications.

With a population of more than 2 million, Manaus is the capital and largest city of the state of Amazonas in the North Region of Brazil, founded in 1693. Manaus is located in the middle of the Amazon rainforest, at the confluence of the Negro and Solimões rivers. Access to the city is primarily by boat or airplane.

This isolation helped preserve both the nature as well as the culture of the city. The city is the main entrance to visit the fauna and flora of the Brazilian Amazon. Few places in the world afford such a variety of plants, birds, insects, and fishes.


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Fundafcao Alfredo Da Matta opened it's doors for master class participants.

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Bem Vindos to Master Class on Vitiligo ad Pigmentary Disorders in Manaus, Brazil!

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Prof. Marcelo Mira opened the program with presentation on genetic risk factors in vitiligo.

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Over 100 participants registered for the intensive program.

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Prof. Paulo Cunha has discussed new vitiligo treatments with piperine, followed by presentation on treatment of melasma with laser.

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Prof. Carolina Talhari talks about hypochromic actinic dermatoses.

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Presentation sparked an active discussion led by Prof. Carlos Machado.

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Prof. Torello Lotti discussed treatment of vitiligo in pediatric age.

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Prof. Mauricio Martins (left) and Joel Carlos Lastoria (right)

Where: Manaus, Brazil
When: Friday, June 10th from 9:00-18:00
Organizers: Paulo Cunha (SP) and Sinésio Talhari (AM)

Official Program

08:50-09:00 - Symposiaum Opening – Carla Ribas (Pres. SBD – Regional AM) and Francisco Helder Cavalcante (Director FUAM)
09:00-09:25 – Genetic risk factors for susceptibility to vitiligo. Marcelo Mira (PR)
09:25-09:50 – Bio-informatics and Bio-banking for research in vitiligo. Yan Valle (USA)
09:50-10:15 - Clinical and Therapeutic Approach of Vitiligo, Carlos Machado (SP)

10:15-10:40 - Coffee - Break

10:40-11:05 - Vitiligo: American Academy of Dermatology Comments. Dr. Mauricio Martins (PR)
11:05-11:30 - Vitiligo Home Treatment - How, When, Why. Torello Lotti (Italy)
11:30-11:55 – Vitiligo: New treatment with Black Pepper extract. Paulo Cunha (SP)
11:55-12:10 – Investigaçao laboratorial em pacientes com vitiligo. Joel Carlos Lastoria (SP)
12:10-12:30 - Discussion

12:30-14:00 – Lunch break

14:00-14:25 - Ethno-Botanical Treatments for Vitiligo. Yan Valle (USA)
14:25-14:50 – Melasma: Treatment with Laser and/or LIP. Paulo Cunha (SP) 
14:50-15:15 – Sirtuins Family and Vitiligo - What's the Next Step? Torello Lotti (Italy)

15:15-15:35 – Coffee break

15:35-16:00 – Hypochromic Actinic Dermatoses. Carolina Talhari/ Antonio Pedro M. Schettini (AM)
16:00-16:25 - Refractory Vitiligo: Treatment with Fractional Carbon Dioxide Laser (CO2) Combined with Betamethasone and Salycilic Acid Solution. Paulo Cunha (SP)
16:25-16:50 - Treatment of Vitiligo in Pediatric Age. Torello Lotti (Italy)
16:50-17:30 - Clinical Cases of Vitiligo: 4 cases (10 minutes each. SinésioTalhari (AM), Mauricio Martins (PR), Joel Carlos Lastoria (SP), Oswaldo Delfini Filho (SP)). Coordinator Oswaldo Delfini Filho (SP).

17:30-18:00 – Discussion and Session Closure.

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Notes on ethnobotanical treatments

During the last decades, new methods of therapeutic research, ethno-botany and ethno-pharmacology and even archeo-pharmacology, have been used extensively to explore 'traditional medicines.' Indigenous cultures possess notions, to a remarkable extent, of indications or applicability of different plants for different diseases, as well as toxicity, contraindications, and interaction among many plants.

However, ‘traditional healers’ and patients do not consider herbals to be pharmacologic, which also have proven potential to significantly interact with prescribed conventional medications. Only few of dozens of “traditional medicines” or “natural remedies” have been observed to be effective in skin diseases, while many are proven to have toxic properties.

Partial relief was achieved in psoriasis, dermatophytoses, ichthyosis, leprosy, and systemic lupus erythematosus (SLE). Some forms of alopecia, onychomycosis, vitiligo, allergic dermatoses, are largely not improved by herbal medicines. It was shown in clinical studies that most effective for vitiligo and pigmentary disorders are extracts of Polypodium leucotomos, Ginkgo biloba and Pyrostegia venusta. 

While not inclusive, participants have received the reference data on the active ingredients, side effects, potential interactions between herbal supplements and conventional medications.

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