Question 8. Is it true that vitiligo can be a part of one of the ...?

Key points

  • Vitiligo may be associated with other disorders.
  • The Dermatologist, in cooperation with Geneticists and Experts in other related fields must properly manage each and every associated/isolated condition.
  • Subjects with vitiligo may also be affected by a multi-system organ dysfunction.
  • The latter are named “vitiligo systemic syndromes”.
  • Usually these cases are discovered at birth or during infancy.

Disorders and syndromes possibly associated with vitiligo (in alphabetical order)

More common associations

  • Addison disease
  • Alopecia areata
  • Atopic dermatitis
  • Autoimmune thyroid disease
  • Chronic urticaria
  • Diabetes mellitus
  • Halo nevi
  • Hypoacusis
  • Hypoparathyroidis
  • Ichthyosis
  • Morphea
  • Ocular abnormalities
    Pernicious anemia
  • Psoriasis
  • Rheumatoid arthritis

Less common associations

  • Acrokeratosis paraneoplastica
  • Ba-zex
  • Alezzandrini syndrome
  • APECED* syndrome (*Autoimmune PoliEndocrinopaty Candidiasis Ectodermal Dysplasia)
  • Asthma
  • Ataxia-telangiectasia
  • Deafness
  • DOPA-responsive dystonia
  • Dysgammaglobulinemi
  • Hemolytic Anemia (autoimmune)
  • Hepatitis C
  • HIV
  • Inflammatory bowel disease
  • Kabuki syndrome
  • Kaposi sarcoma
  • Lymphoma
  • Melanoma
  • MELAS syndrome
  • Morphea
  • Multiple sclerosis
  • Myasthenia gravis
  • Nonmelanoma skin cancer
  • Nail distrophy
  • Pemphigus vulgaris
  • Sarcoidosis
  • Schmidt syndrome
  • Systemic lupus erythematosus
  • Turner syndrome
  • Twenty-nail dystrophy
  • Vogt-Koyanagi-Harada syndrome

Author: Prof. Torello Lotti, MD

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