Question 9. Is there a full list of white patches on skin...?

Question 9. Is there a full list of white patches on skin, which are not associated with vitiligo?

Key points

  • Not all white patches on the skin are a sign of vitiligo. White patches not diagnosed as vitiligo are named leukodermas.
  • A list of the so-called leukodermas is available for Dermatologists who face the problem differentially diagnosing vitiligo.
  • An expert Dermatologist should be able to recognize all cases of leukodermas.
  • Different kinds of leukoderma require different treatments.

Not all white spots appearing on the skin are vitiligo. White patches that are not diagnosed as vitiligo are named leukodermas.

Here is a list of leukodermas for dermatologic use:

  • Chemically-induced leukoderma (often occupational): Arsenic; Phenols and other derivatives, cathecols Infections: Leishmaniasis (post kala-azar); Leprosy; Onchocerciasis; Secondary siphylis; Tinea versicolor; Treponematoses (pinta and syphilis)
  • Genetic syndromes: Chediac-Higashi syndrome; Hypomelanosis of Ito; Oculocutaneous albinism; Piebaldism; Tuberous sclerosis; Vogt-Koyanagi-Harada syndrome; Waardenburg syndrome
  • Postinflammatory hypopigmentation: Atopic dermatitis/allergic contact dermatitis; Nummular dermatitis; Phototherapy- and radiotherapy-induced hypopigmentation; Pityriasis alba; Postraumatic hypopigmentation (scar); Psoriasis; Sarcoidosis; Systemic lupus erythematosus; Topical or systemic drug-induced depigmentation
  • Neoplastic: Amelanotic melanoma; Halo nevus; Melanoma-associated leukoderma; Mycosis fungoides
  • Idiopathic: Idiopathic guttate hypomelanosis; Lichen sclerosus et atrophicus; Lichen striatuslike leukoderma; Morphea; Melasma (caused by contrast between lighter and darker skin); Progressive (or acquired) macular hypo-melanosis
  • Malformations: Nevus anemicus; Nevus depigmentosus/hypopigmentosus; Nutritional; Kwashiorkor; Selenium deficiency

Author: Prof. Torello Lotti, MD

Please be advised that all information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. You should seek prompt medical care for any specific health issues and consult your physician or health practitioner. Users are warned against changing any aspects of their treatment, diet or lifestyle based on this information without first consulting a registered medical practitioner. While every precaution is taken to ensure accuracy, VR Foundation makes no warranty as to the reliability, accuracy, timeliness, usefulness or completeness of the content which reflect personal opinion of the authors.

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