Overview of Vitiligo Research April - June 2015


  • Janus kinase inhibitors, in particular, tofacitinib, emerge as a novel treatment modality for vitiligo.
  • A review of recent advances in nano- and micro-particles designed for improved topical delivery of bioactive substances. 
  • A novel molecular link between oxidative stress in vitiligo and promotion of immune cell-mediated melanocyte destruction has been suggested.
  • Genetic variation might be useful to predict efficiency of narrow-band ultraviolet B treatment of vitiligo.
  • A confetti-like depigmentation might be considered as a negative prognostic factor in vitiligo patients.
  • Psychological stressors should be considered as possible vitiligo triggers.
  • Pyrostegia venusta leaf extract, a native Brazilian plant, showed anti-inflammatory and hyperpigmenting effects, thus providing a rational for its beneficial effects for vitiligo.
  • Hand-held 'black light', which is readily available from online stores, can be used instead of specialized Wood’s lamp for vitiligo diagnosis.
  • A low-dose cytokine treatment result in substantial repigmentation in vitiligo patients, especially when combined with microphototherapy.
  • A traditional Iranian cosmetic formulation 'sabgh' can serve as an alternative to cosmetic camouflage products designed for vitiligo.

This is a review of research results in the vitiligo field which were indexed in the PubMed database for the period from April 2015 till June 2015. Abstracts of papers were retrieved from the PubMed database using the search term “vitiligo” with a filter set up to retrieve records with creation date between April 01, 2015 and June 30, 2015. Retrieved records were manually checked for a relevance to and significance for the field of vitiligo research. Forty six records were found to be relevant and of interest, and were included in this quarterly overview.

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