Overview of Vitiligo Research January - March 2015
- Research found increased incidence of vitiligo among psoriasis patients, and vice versa, thus suggesting common factors and mechanisms contributing to these diseases.
- CCL22 molecule which promotes regulatory T-cell homing to skin emerges as a candidate for rational-based vitiligo therapy development.
- Intrinsic defects in melanocyte cell adhesion secured by E-cadherin protein might be a factor predisposing to vitiligo.
- CO2 laser combined with topical betamethasone and narrow-band ultraviolet B can be an efficient treatment option of vitiligo in hard-to-repigment locations.
- Involvement of Th17 cells in vitiligo pathogenesis is getting more experimental support.
- A case of vitiligo onset apparently caused by atomoxetine, a drug used to treat attention deficit/hyperactivity disorder, has been documented.
- Two studies confirmed that vitiligo onset in melanoma patients is a good prognostic factor of melanoma treatment success likely witnessing successful activation of anti-tumor immunity.
- Comparison of home-based phototherapy with institution-based 308 nm excimer lamp for the treatment of focal vitiligo vulgaris hints better prospects of home-based treatments.
This is a review of research results in the vitiligo field which were indexed in the PubMed database (www.ncbi.nlm.nih.gov/pubmed) for the period from January 2015 till March 2015. Abstracts of papers were retrieved from the PubMed database using the search term “vitiligo” with a filter set up to retrieve records with creation date between January 01, 2015 and March 31, 2015. Retrieved records were manually checked for a relevance to and significance for the field of vitiligo research. Fifty nine records were found to be relevant and of interest, and were included in this quarterly overview, under the following sections:
- Reviews & Comments
- Disease Management And Clinical Features
- Quality of life (QoL)
- Vitiligo triggers
- Case reports
- Understanding mechanisms of vitiligo pathogenesis
- Genetic studies
- Candidate biomarkers
- Mechanisms of treatments
- Methodological advancements
- Novel treatment modalities
- Clinical studies and trials
I support the petition to designate June 25 as Vitiligo World Day and save millions of people worldwide from social isolation and persecution.
What is coming?
XXIII Master Class in Cuba
will be held as a part of INDERCOS Winter Meeting, in collaboration with Cuban Vitiligo Support and Research Group. International and national expert speakers will di...16 November 2017 09:00, Hotel Nacional de Cuba, Habana, Cuba
High-level Meeting on the Asian and Pacific Decade of People With Disabilities
The UN's Economic and Social Commission for Asia and the Pacific (ESCAP), in cooperation with the China Disabled Persons’ Federation (CDPF), is organizing the High-lev...27 November 2017 09:00, Beijing, China
What causes vitiligo?
The precise cause of vitiligo is not well understood. The white areas appear due to loss of the pigment (melanin) that gives skin its color and protects it from the su...
Why there is no drug for vitiligo yet?
Despite the dearth of medications available to treat psoriasis - a disease with similar prevalence numbers and impact on quality of life - vitiligo has no known cure o...
Is there a traditional medicine to treat vitiligo?
During the last decades, new methods of therapeutic research, ethno-botany and ethno-pharmacology and even archeo-pharmacology (PubMed), have been used extensively to ...
What is vitiligo?
Vitiligo (pronounced vit-ill-EYE-go) is a relatively common skin disease characterized by smooth, white, painless spots or patches on various parts of the body. It doe...