Overview of Vitiligo Research October - December 2014
- Vitiligo Screening Tool (VISTO) is a simple, cost-effective, self-administered tool to confirm vitiligo.
- Much lower prevalence of vitiligo and later disease onset among Taiwanese population is reported (0.064%).
- Serum BDNF may be linked to repeatedly reported association of vitiligo with psychiatric disorders.
- Unexpectedly, IL-2 and IL- 6 levels hint at different mechanism of pathogenesis of stress-induced vitiligo.
- Analogue of viral DNA can trigger melanocyte death, which hints at possible contribution of viruses to vitiligo onset.
- Simvastatin is showing potency to reverse and prevent vitiligo in an experimental mouse model.
- Topical latanoprost (prostaglandin F2-alpha analogue) can be used (alone or in combination with NB-UVB phototherapy) to induce repigmentation of vitiligo lesions
- Infrequent topical tacrolimus can be used as prophylactics to prevent relapse after successful repigmentation
- Based on results of study in mice, simvastatin emerges as a novel treatment for vitiligo, capable to prevent vitiligo onset and to reverse already manifested disease
- Ethnical difference in vitiligo prevalence and associated comorbidities profiles has been further confirmed.
- Level of reactive oxygen species in erythrocytes emerges as an indicator of vitiligo activity.
- Involvement of regulatory T-cell abnormalities in vitiligo pathogenesis is gaining more support.
This is a review of research results in the vitiligo field which were indexed in the PubMed database (www.ncbi.nlm.nih.gov/pubmed) for the period from October till December 2014. Retrieved records were manually checked for a relevance to and significance for the field of vitiligo research. Fifty one records were found to be relevant and of interest, and were included into this quarterly overview, under the following sections:
- Reviews & Comments
- Disease Management And Clinical Features
- Quality of life (QoL)
- Vitiligo triggers
- Case reports
- Understanding mechanisms of vitiligo pathogenesis
- Genetic studies
- Candidate biomarkers
- Mechanisms of treatments
- Methodological advancements
- Novel treatment modalities
- Clinical studies and trials
I support the petition to designate June 25 as Vitiligo World Day and save millions of people worldwide from social isolation and persecution.
What is coming?
Master Class On Vitiligo In Pediatric Age
will be held alongside “International Forum on Paediatric Dermatology”, which will take place in Rome (Italy), on October 5-7, 2017. This is an exciting opportunity t...06 October 2017 09:00, P.zza Giovanni Randaccio, 1 - Rome...
Master Class On Vitiligo alongside the World Congress Of Dermatology
The Italian Society of Dermatology will host the 24th World Congress of Dermatology in Milan, Italy, under the auspices of the International League of Dermatological ...10 June 2019 09:00, Milan, Italy
What tests should be done?
No tests are usually necessary to make the diagnosis. The white patches may be seen more easily under Wood's light examination.
Who is prone to vitiligo?
Vitiligo affects 0.5-2% of the population, and occurs in all races and all social levels. Vitiligo can affect people of all ages, but often starts between the ages of ...
Pyrostegia venusta as a folk medicine for vitiligo?
Pyrostegia venusta is a neotropical evergreen vine widely spread in Brazil throughout fields, at the coast, edge of the woods and along roadsides (see photo below). Po...
What causes vitiligo?
The precise cause of vitiligo is not well understood. The white areas appear due to loss of the pigment (melanin) that gives skin its color and protects it from the su...