Overview of Vitiligo Research Jan - Mar 2014

This is our exclusive quarterly review of research results in the vitiligo field for the period from January till March 2014 published April 10, 2014.

Highlights

  • Simple leaflet including psychoeducation, relaxation and attentional refocusing combined with guidance on forming specific “if-then” plans might be an effective tool to alleviate social anxiety in vitiligo patients.
  • Acridone acetic acid emerges as a novel treatment of vitiligo bringing effective and long-lasting cessation of disease activity. Oral minocycline shows up as an equally efficient alternative to systemic steroids in the management of active vitiligo.
  • Novel topical formulation emulating NB-UVB phototherapy upon sun exposure showed efficacy in the treatment of vitiligo.
  • Long-term topical use of nitrogen mustard to treat vitiligo may lead to development of multiple skin malignancies.
  • High-dose daily vitamin D combined with low calcium diet showed promising results in the treatment of vitiligo in a pilot clinical trial.
  • Two studies reported that topical 0.1% tacrolimus is as effective as NB-UVB phototherapy thus suggesting that topical 0.1% tacrolimus may be an alternative to NB-UVB phototherapy.
  • Repigmentation response to different topical treatment modalities might vary in one and the same patient.

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