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Official Title: Efficacy and Tolerance of the Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo: a Randomized Double-blind Prospective Study
Brief Summary: This is a phase 2, randomized, double blind, multicenter study evaluating the efficacy and safety of the combination of methotrexate plus UVB TL01 in vitiligo.
Detailed Description: Treatment Strategy: Multicentric, parallel double blind randomized phase 2 prospective study comparing MTX taken orally once a week + narrowband UVB TL01 versus placebo + narrowband UVB TL01 Follow-up of the study: patients included in this study will start MTX 2 months before starting narrowband UVB TL01. Phototherapy will be performed twice a week during 6 months. Follow-up visit will be done at month 2, 4 and month 8. Phone calls to the patient will be done at month 6.
Estimated Study Start Date: June 2, 2022
Estimated Study Completion Date: February 27, 2023
Contact:
- Julien SENESCHAL, MD, PhD
+335 56 79 49 63
julien.seneschal@chu-bordeaux.fr
- Sitraka RASOLOFO
+335 56 82 06 55
sitraka.rasolofo@chu-bordeaux.fr
https://beta.clinicaltrials.gov/study/NCT04237103
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