Baltimore, USA - 01 Sep `17Early Molecular Changes After NB-UVB

Official Title: Early Molecular Changes in Vitiligo After Narrowband Ultraviolet Therapy

In Brief: This is an investigator-initiated, single-blinded, ascending dose study of NB-UVB treatment for vitiligo in adults of 3 treatments for one week. It is designed to measure the molecular changes and re-pigmentation in affected and normal skin of participants with vitiligo and normal skin in healthy participants. Participants diagnosed with vitiligo who are enrolled in the study will receive phototherapy (NB-UVB), with the starting dose of 250 mJ/cm2. The dose will be increased by 10% with each treatment. Small skin samples will be collected before and after NB-UVB treatment.

Ages Eligible: 18 Years to 100 Years

Start Date: September 1, 2017 

Completion Date (estimated): September 1, 2022

Status: Active, recruiting

Study ID from ClinicalTrials.gov: NCT03270241

Location: Johns Hopkins Outpatient Center, Baltimore, Maryland, United States, 21287

Contact: To learn more about this study, you or your doctor may contact Ruizhi Wang by phone +1-410-502-7546 or email CTReP@jhmi.edu. Please refer to this study by its NCT number.

FAQOther Questions

  • Is there a special diet for vitiligo?

    In short, no.  Some people find that certain foods may worsen their vitiligo symptoms or that others may improve their skin condition. We found no scientific evidence that a sp...

  • What causes vitiligo?

    Surprisingly, the causes of vitiligo are yet to be precisely established. Researchers know the cause is pre-wired in your genes, just waiting for a bad luck moment. In about hal...

  • Will it spread?

    Vitiligo activity may vary considerably from person to person. The natural course of vitiligo is truly unpredictable but usually progressive. The most recent VALIANT study on v...