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Official Title: Early Molecular Changes in Vitiligo After Narrowband Ultraviolet Therapy
In Brief: This is an investigator-initiated, single-blinded, ascending dose study of NB-UVB treatment for vitiligo in adults of 3 treatments for one week. It is designed to measure the molecular changes and re-pigmentation in affected and normal skin of participants with vitiligo and normal skin in healthy participants. Participants diagnosed with vitiligo who are enrolled in the study will receive phototherapy (NB-UVB), with the starting dose of 250 mJ/cm2. The dose will be increased by 10% with each treatment. Small skin samples will be collected before and after NB-UVB treatment.
Ages Eligible: 18 Years to 100 Years
Start Date: September 1, 2017
Completion Date (estimated): September 1, 2022
Status: Active, recruiting
Study ID from ClinicalTrials.gov: NCT03270241
Location: Johns Hopkins Outpatient Center, Baltimore, Maryland, United States, 21287
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