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Official Title: Early Molecular Changes in Vitiligo After Narrowband Ultraviolet Therapy
In Brief: This is an investigator-initiated, single-blinded, ascending dose study of NB-UVB treatment for vitiligo in adults of 3 treatments for one week. It is designed to measure the molecular changes and re-pigmentation in affected and normal skin of participants with vitiligo and normal skin in healthy participants. Participants diagnosed with vitiligo who are enrolled in the study will receive phototherapy (NB-UVB), with the starting dose of 250 mJ/cm2. The dose will be increased by 10% with each treatment. Small skin samples will be collected before and after NB-UVB treatment.
Ages Eligible: 18 Years to 100 Years
Start Date: September 1, 2017
Completion Date (estimated): September 1, 2022
Status: Active, recruiting
Study ID from ClinicalTrials.gov: NCT03270241
Location: Johns Hopkins Outpatient Center, Baltimore, Maryland, United States, 21287
- What tests should be done?
A well-trained dermatologist should be able to diagnose vitiligo and distinguish it from contact leukoderma or more than twenty other conditions with similar skin appearance bas...
- Who is prone to vitiligo?
Scientists know that some people are genetically predisposed to a specific group of autoimmune diseases – including generalized vitiligo – but do not know who and why.It doesn’t...
- I have vitiligo: will my children have vitiligo, too?
Children born to parents who both have the disorder are more likely to develop vitiligo. However, most children will not get vitiligo even if one parent has it. In children wit...
Though it is not always easy to treat vitiligo, there is much to be gained by clearly understanding the diagnosis, the future implications, treatment options and their outcomes.
Many people deal with vitiligo while remaining in the public eye, maintaining a positive outlook, and having a successful career.Copyright (C) Bodolóczki Júlia
By taking a little time to fill in the anonymous questionnaire, you can help researchers better understand and fight vitiligo.