Yonsei, REPUBLIC OF KOREA - 30 Aug `18Investigation on the Expression of HMGB1

Official Title: The Investigation on the Expression of High Mobility Group Protein Box-1 (HMGB1) in Peripheral Blood of Vitiligo Patients and Healthy Controls According to Clinical Features, Treatment and Disease Activity

In Brief: Vitiligo is an acquired depigmented disorder that causes white spots on the skin due to the loss of melanocytes. It is a common disease which accounts for 0.5-1% of the whole population. It is a refractory skin disease with 25-50 thousand patients in Korea. And it is often caused in the exposed areas of the patient, causing a great deal of mental and social dysfunction in the patient's life, and may lead to suicide attempts.

Ages Eligible: 19 Years and older

Start Date: August 30, 2018

Completion Date (estimated): August 29, 2020

Status: Active, recruiting

Study ID from ClinicalTrials.gov: NCT03741738

Location: Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea, 03722

Contact: To learn more about this study, you or your doctor may contact Sang Ho Oh, MD, PhD by phone +82 2 2228 2080 or email oddung93@yuhs.ac. Please refer to this study by its NCT number.

FAQOther Questions

  • Vitiligo and hearing loss: any connection?

    In short, NO. Recent research shows no relationship between a degree of skin depigmentation and hearing loss severity in vitiligo patients. The results of this study showed tha...

  • Isn't it just a cosmetic disorder?

    Contrary to popular belief, vitiligo is not a cosmetic disorder but a systemic disease affecting the largest body organ and other vital systems, with multiple comorbidities. Fo...

  • Who is prone to vitiligo?

    Scientists know that some people are genetically predisposed to a specific group of autoimmune diseases – including generalized vitiligo – but do not know who and why.It doesn’t...