Can Scenesse be used for vitiligo treatment?
The drug Scenesse from Clinuvel has been tested in clinical trials in relation vitiligo. Profs. Henry Lim, Mark Lebwohl and coauthors reported (PubMed) results of multicenter Phase I clinical trials of Afamelanotide in combination with narrowband UVB. Authors noticed faster and better repigmentation in experimental group compared to the control group receiving only NB-UVB, yet this effect was limited to dark skin types (type IV-VI) but not for type III skin or lighter.
The new drug acts as an anti-oxidant and activates melanin in skin, which in turn increases pigmentation of the skin and provides barrier from harmful UV rays. The benefits are a decrease in light sensitivity, and a limited increase in time EPP patients may spend in daylight. The most common side effects are headache, nausea, nasopharyngitis, migraine, abdominal pain, fatigue, lethargy and somnolence.
Each 16mg implant costs around $6,200 and lasts 60 days.
Under current EMA approval, Scenesse will be closely monitored under a “pharmacovigilance” plan to ensure the treatment remains effective and there is no off-label usage. Despite not being currently approved for vitiligo, this drug may be one of the treatment options for some vitiligo sufferers down the road.
I support the petition to designate June 25 as Vitiligo World Day and save millions of people worldwide from social isolation and persecution.
What is coming?
Master Class On Vitiligo In Pediatric Age
will be held alongside “International Forum on Paediatric Dermatology”, which will take place in Rome (Italy), on October 5-7, 2017. This is an exciting opportunity t...06 October 2017 09:00, P.zza Giovanni Randaccio, 1 - Rome...
Master Class On Vitiligo alongside the World Congress Of Dermatology
The Italian Society of Dermatology will host the 24th World Congress of Dermatology in Milan, Italy, under the auspices of the International League of Dermatological ...10 June 2019 09:00, Milan, Italy
What's better: laser or phototherapy?
In a recent controlled study researchers assessed effect and safety of different laser and phototherapy treatments, such as excimer laser/light, narrowband UVB, UVA an...
How long does it take to treat vitiligo?
Treatment results will vary by person and type of vitiligo. The rule of thumb is that you will need to allow at least 3 to 6 months before you begin to see results fro...
Is there a special diet for vitiligo?
We have specifically looked into claims that some food supplements or special diet may ease symptoms of vitiligo, or completely reverse it, and found no firm scientifi...
How to get insurance coverage for vitiligo treatments?
Most of health insurance companies will initially reject claims for vitiligo doctor visits or phototherapy treatments but with enough efforts you can have a substantia...