Pyrostegia venusta as a folk medicine for vitiligo?
Pyrostegia venusta is a neotropical evergreen vine widely spread in Brazil throughout fields, at the coast, edge of the woods and along roadsides (see photo below). Popularly known as “flame vine” or “cipó-de-são-joão”, this species is cultivated due to its outstanding ornamental features and due its important therapeutic properties (abstract).
P. venusta leaves and stems are used in traditional medicine as a tonic or antidiarrheal agent, while its flowers are used in the treatment of leucoderma and vitiligo (abstract). It is also used as anti-inflammatory medicine in cough and common diseases of the respiratory system, such as bronchitis, flu and cold (Ferreira et al., 2000, Scalon et al., 2008 and Veloso et al., 2010). Extracts of flowers and roots of P. venusta contain significant amounts of phytochemicals with antioxidative properties that could act as inhibitors or scavengers of free radicals. It is a one of the most prolific sources of flavonoids.
Although pre-clinical and other studies clearly demonstrate the antiinflammatory and hyperpigmentant activities of P. venusta, questions about it's in vivo efficacy remain unclear. In fact, many other melanogenesis stimulators found in the in vitro studies failed to show in vivo efficacy, probably because they could not reach outer skin cells from within because of the stratum corneum barrier.
Further clinical research is needed to examine whether topically applied P. venusta can enhance skin pigmentation, and whether it could be used as a potential source for plant-based pharmaceutical products for vitiligo.
Brazil not only has one of the world’s highest levels of biodiversity, but also it has an under-used repertoire of plants with potential medicinal and economic value.
Photo ©Pedro Acevedo-Rodriguez.
Pyrostegia venusta is a common sight alongside roads and fields in Brazil.
I support the petition to designate June 25 as Vitiligo World Day and save millions of people worldwide from social isolation and persecution.
What is coming?
NY Vitiligo Community Meeting in September
Our next meeting will be on Thursday, September 21st, at 7PM - 8:30PM on the 11th floor of NYU's Ambulatory Care Center at 240 East 38th Street, between 2nd and 3rd Av...21 September 2017 19:00, 11th floor of NYU's Ambulatory Car...
Vitiligo Advocacy Day at the US Capitol
Save-the-Date for the much anticipated Vitiligo Advocacy Day at the United States Capitol this fall. As many of you know, the Advocacy Committee of the Global Vitilig...04 October 2017 10:00, Washington, DC
Isn't it just a cosmetic disorder?
Like it or not, we live in a society where appearance matters. It should come as no surprise that vitiligo impacts on the psychological well-being and quality of life ...
Can Ginkgo Biloba help with vitiligo?
Ginkgo Biloba extract seems to be a simple, safe and fairly effective therapy for arresting the progression of the vitiligo. Ginkgo Biloba is known to have anti-inflam...
I have vitiligo: will my children have vitiligo, too?
In some cases vitiligo seems to be inherited and run in families, with children whose parents have vitiligo being at increased risk of developing the condition themsel...
Are there any famous people with vitiligo?
Many celebrities have dealt with vitiligo while remaining in the public eye, maintaining a positive outlook, and having a successful career. Here are a few courageous ...