Publication - 2015Application of peptidoglycan with immunomodulating activity in vitiligo therapy

Publication

Application of peptidoglycan with immunomodulating activity in vitiligo therapy

We study the efficiency of acid peptidoglycan ofplant origin with immunomodulatory activity in therapy of vitiligo. Twenty-five patients with active vitiligo received a course of treatment (6 injections). The activity of vitiligo was evaluated after 1, 3, and 6 months of the therapeutic course. The results were compared with the patients’ clinical and immunological data before therapy. Disease stabilization was attained 6 months after therapy in 18 (72%) patients. Low secretion of phytohemagglutinin-induced IFN-g by peripheral blood mononuclears before therapy seemed to be a prognostic factor predicting active course of vitiligo after therapy. Hence, use of acid peptidoglycan with immunomodulatory activity can be regarded as a new safe and effective method for vitiligo progress.

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Korobko IV, Lomonosov KM



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