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Publication
Application of peptidoglycan with immunomodulating activity in vitiligo therapy
We study the efficiency of acid peptidoglycan ofplant origin with immunomodulatory activity in therapy of vitiligo. Twenty-five patients with active vitiligo received a course of treatment (6 injections). The activity of vitiligo was evaluated after 1, 3, and 6 months of the therapeutic course. The results were compared with the patients’ clinical and immunological data before therapy. Disease stabilization was attained 6 months after therapy in 18 (72%) patients. Low secretion of phytohemagglutinin-induced IFN-g by peripheral blood mononuclears before therapy seemed to be a prognostic factor predicting active course of vitiligo after therapy. Hence, use of acid peptidoglycan with immunomodulatory activity can be regarded as a new safe and effective method for vitiligo progress.
Korobko IV, Lomonosov KM
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