PatientsAbout Vitiligo

About Vitiligo

Copyright © Stephanie Corne. Used with permission

Vitiligo (pronounced vit-ill-EYE-go) is a skin condition characterized by the gradual loss of pigment in certain areas of the skin, and sometimes in the hair above those areas. This occurs when the immune system mistakenly attacks melanocytes—the cells responsible for producing skin pigment—resulting in white patches that can appear anywhere on the body.

Although vitiligo is a lifelong condition with an unpredictable course, it is neither harmful to overall health nor contagious. With a proper diagnosis, an individualized treatment plan, and regular follow-up care, it is often possible to manage the condition effectively and reduce the visibility of white patches.

  • Treatment Options and Strategies for Vitiligo Patients diagnosed with vitiligo face three primary management approaches: attempting to restore pigmentation through medical treatment, using cosmetic camouflage to conceal depigmented areas, or ...
  • The underlying cause of vitiligo is rooted in genetics, with the condition often "pre-wired" and waiting for a triggering event. In about half of all cases, a specific trigger or an unfortunate combination of seemingly harmless factors initiates t...
  • The prevalence of vitiligo varies widely across the globe, with estimates ranging from 0.004% to 2.28% of the population, and even higher in certain regions. A consensus among researchers places the prevalence closer to 1% of the global population...
  • Current Understanding of Vitiligo Pathogenesis Despite decades of intensive research, the precise etiology of vitiligo remains partially elusive. The scientific consensus describes it as a multifactorial disorder resulting from a complex converge...
  • The hallmark of vitiligo is the appearance of distinct, pale, or milky-white patches on the skin. These patches—medically termed macules—are typically flat, non-scaly, and painless. While the loss of pigment is the most visible sign, the condition...
  • Vitiligo has been recognized for over 4,000 years, with early references found in ancient texts and cultures worldwide. The Rig Veda (~1500 BC) described depigmentation as "Kilas," likened to a white-spotted deer. Ancient Egyptian records (Ebers P...
  • Vitiligo treatment typically involves a year-long course of therapy, and interruptions of even a month may necessitate restarting the treatment. Before committing to a long-term plan, it’s essential to assess the financial resources required. Belo...

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Whichever track you took through this website, you now have a better overview of vitiligo than 99% of people who live with it, or are helping a family member who has vitiligo.

If you are interested in taking part in clinical trials of new therapies, visit our Trial Hub. Information is provided by the U.S. National Institutes of Health and updated here on a monthly basis.

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Please be advised that all information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. Users are warned against changing any aspects of their treatment, diet or lifestyle based on this information without first consulting a registered medical practitioner. While every precaution is taken to ensure accuracy, VRF makes no warranty as to the reliability, accuracy, timeliness, usefulness or completeness of the content which reflect personal opinion of the authors.