The underlying cause of vitiligo is rooted in genetics, with the condition often "pre-wired" and waiting for a triggering event. In about half of all cases, a specific trigger or an unfortunate combination of seemingly harmless factors initiates the condition. In the other half, the exact cause remains unknown.

Psychological stress is the most frequently reported trigger for vitiligo. Severe sunburn, physical skin damage, prolonged contact with certain chemicals may induce or worsen vitiligo. Hormonal changes during pregnancy, delivery and menopause may be the culprit. Parasites and chronic gastritis that impair absorption of vital elements by the digestive system may also indirectly cause vitiligo.

Specific chemicals have been identified as potential contributors to vitiligo, particularly in those predisposed to the condition. These include:

• p-phenylenediamine (PPD): Found in many hair dyes or temporary tattoos.
• para-tertiary butylphenol (PTBP): Used in cosmetics, cleansers, and perfumes.
• Monobenzylether of hydroquinone (MBH): Present in some industrial products.

Exposure to these chemicals is common in everyday items such as detergents, insecticides, black rubber products (e.g., slippers, condoms, or shoes), motor oil additives, germicidal soaps, and printed inks.

While the triggers may vary, vitiligo likely results from a combination of genetic predisposition and environmental factors.

Continue reading:

• The Hidden Danger of Cosmetics: Vitiligo and Other Skin Problems
• Tattoo Ink and Vitiligo: A Cautionary Case of Systemic Reaction to Red Ink