Publication - 2022Using methotrexate in the treatment of advanced vitiligo

Publication

Methotrexate has shown potential as a treatment for advanced vitiligo, particularly in cases of rapidly progressing or unstable disease. It works by interfering with DNA synthesis and inducing apoptosis in active CD4+ T cells, while also reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines.

Alana Tavitova, Yan Valle, Konstantin Lomonosov



FAQOther Questions

  • Which diseases most commonly accompany vitiligo?

    Vitiligo is an autoimmune disease and is frequently associated with other autoimmune diseases, acccording to a 10-year study. The exact diseases that accompany vitiligo can vary...

  • Shall I take vitamin D for my vitiligo?

    Vitamin D plays a central role in the prevention of different inflammatory and chronic diseases. Consuming 1,000–4,000 IU (25–100 mcg) of vitamin D3 daily should be ideal for mo...

  • Who is prone to vitiligo?

    Vitiligo can affect anyone, regardless of gender, age, or race. Vitiligo prevalence is between 0.76% and 1.11% of the U.S. population, including around 40% of those with the con...