Publication - 2022Using methotrexate in the treatment of advanced vitiligo

Publication

Methotrexate has shown potential as a treatment for advanced vitiligo, particularly in cases of rapidly progressing or unstable disease. It works by interfering with DNA synthesis and inducing apoptosis in active CD4+ T cells, while also reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines.

Alana Tavitova, Yan Valle, Konstantin Lomonosov



FAQOther Questions

  • Are there any famous people with vitiligo?

    Many celebrities have dealt with vitiligo while remaining in the public eye, maintaining a positive outlook, and having a successful career. Here are a few courageous famous peo...

  • Is there a link between vitiligo and depression?

    Depression and anxiety are often linked with vitiligo, significantly impacting a person’s quality of life. The connection stems from the shared origin of the skin and brain duri...

  • Can chemicals cause vitiligo?

    Certain chemicals can trigger vitiligo, leading to a condition known as chemical-induced vitiligo. While clinically and histologically indistinguishable from other types of viti...