Publication - 2025Unraveling genetic predisposition and oxidative stress in vitiligo development and the role of artificial intelligence (AI) in diagnosis and management

Publication

This paper presents an overview of vitiligo as an autoimmune disorder with a complex genetic background, highlighting how artificial intelligence (AI) is transforming its diagnosis and treatment. Researchers have identified around 50 genes linked to vitiligo, many involved in immune response, cell death, and pigment production, with inflammation and oxidative stress playing key roles. AI-driven technologies analyze genetic, clinical, and imaging data to enable earlier detection, more precise classification, and personalized treatment strategies. By optimizing therapeutic monitoring and tracking disease progression in real time, AI integration promises to revolutionize vitiligo care and improve patient outcomes.

J Med Biochem 44(2): 1–11 © 2025 by SMBS, Belgrade

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Hristina Kocic, Torello Lotti, Tatjana Jevtovic-Stoimenov, Uwe Wollina, Yan Valle, Stevo Lukic, Aleksandra Klisic



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