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0.005% Latanoprost Gel for Nonsegmental Vitiligo
Official title: Comparison of the Effectiveness Between a Combination of 0.005% Latanoprost Gel With 308 nm Excimer Phototherapy and a Combination of 0.1% Mometasone Furoate Cream With 308 nm Excimer Phototherapy on Repigmentation of Nonsegmental Vitiligo in Children
Status: Opening soon
Description:
Latanoprost, a prostaglandin F2α (PGF2α) analog used for glaucoma treatment, is known to cause iris darkening, hypertrichosis, and periocular skin hyperpigmentation. PGF2α has been shown to stimulate the growth of melanocyte dendrites, increasing dendricity even at low doses, as well as enhancing tyrosinase activity and quantity, thereby promoting repigmentation. Studies on the use of 0.005% latanoprost gel in both children and adults with vitiligo have demonstrated effective repigmentation without reported side effects.
Phase: Phase 2.
What is being studied: drugs — 0.005% latanoprost gel, 0.1% mometasone furoate cream.
Who can take part: ages 10 Years to 17 Years, 10 participants planned.
Enrollment status: the registry has not updated this study since its planned completion date, so its current status is unclear. The study started 01 July 2025 and was due to finish 30 November 2025.
Contact: Safira M Pranata, MD.
Source: ClinicalTrials.gov, NCT07016113 (https://clinicaltrials.gov/study/NCT07016113).
Start date: July 01, 2025
Completion date: November 30, 2025
Organizer: Universitas Padjadjaran
Contact: Safira M Pranata, MD
Tel.: +6281220648003
Email: safira14001@mail.unpad.ac.id
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