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Official Title: A Phase 1, Single and Multiple Ascending Dose (SAD/MAD) Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of VYN201 in Healthy Volunteers and in Subjects with Non-Segmental Vitiligo (NSV)
Brief Summary: A Phase 1 study of VYN201 in Healthy Volunteers and Subjects with Non-Segmental Vitiligo
Detailed Description: Study VY2022-01 is an open-label study of VYN201 ointment given as single and multiple ascending doses in healthy volunteers, followed by multiple dosing of the three highest tolerated dosages in subjects with NSV. The healthy volunteer part has been completed and participants with vitiligo that qualify will be allocated to one of three treatment groups: low-dose VYN201, mid-dose VYN201, or high-dose VYN201.
Actual Study Start Date: November 2022
Estimated Study Completion Date: May 2023
Contact: Vyne Therapeutics
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