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Ritlecitinib for nonsegmental vitiligo
Official title: A PHASE 3 RANDOMIZED, DOUBLE-BLIND, 52-WEEK PLACEBO-CONTROLLED MULTI-CENTER STUDY WITH A DOUBLE-BLIND 52-WEEK EXTENSION PERIOD WITH RANDOMIZED DOSE UP/DOSE DOWN TITRATION INVESTIGATING THE EFFICACY, SAFETY, AND TOLERABILITY OF RITLECITINIB IN ADULT PARTICIPANTS WITH NONSEGMENTAL VITILIGO
Status: Closed to new participants
Description:
Pfizer enrolled about 1,571 participants. Ritlecitinib is an oral immune-modulating drug that blocks JAK3 and TEC-family signaling. Researchers hope it will reduce the immune attack on melanocytes and support repigmentation. Ritlecitinib is sold as Litfulo and is approved for severe alopecia areata in people age 12 and older; vitiligo would be a new use. Possible effects include headache, diarrhea, acne, and infections. People age 18 and older may qualify. The study is underway but is no longer accepting new participants.
Start date: November 08, 2023
Completion date: July 30, 2027
Organizer: Pfizer
Contact: Pfizer CT.gov Call Center
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FAQOther Questions
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Vitamin D plays a central role in the prevention of different inflammatory and chronic diseases. Consuming 1,000–4,000 IU (25–100 mcg) of vitamin D3 daily should be ideal for mo...
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Corticosteroid drugs (like hydrocortisone, and others) are often used for treating vitiligo. By mimicing the effects of hormones your body produces naturally in your adrenal gla...
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