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Comparative Study of Microneedling With Topical Minoxidil 5% ± NB-UVB in Stable Vitiligo"
Official title: Comparative Clinical and Histopathological Study of Microneedling With Topical Minoxidil 5% Versus Microneedling With Topical Minoxidil 5% Combined With Narrow-Band Ultraviolet B Phototherapy in the Treatment of Stable Vitiligo
Status: Opening soon
Description:
This study is a randomized controlled trial comparing microneedling with topical minoxidil 5% versus microneedling with minoxidil combined with NB-UVB phototherapy in stable vitiligo. It aims to evaluate both clinical and histopathological outcomes in 30 patients with non-segmental stable vitiligo. Vitiligo is a chronic depigmenting disorder caused by melanocyte destruction with significant psychosocial impact. The study also investigates immunohistochemical changes, particularly Wnt/β-catenin signaling expression in lesional skin. The combination therapy is expected to enhance repigmentation by improving melanocyte activation, drug delivery, and angiogenesis
Phase: Phase 2.
What is being studied: combination products — microneedling with minoxidil 5% and NBUVB, Microneedling with Minoxidil5%.
Who can take part: ages 16 Years to 60 Years, 30 participants planned.
Enrollment status: Opening soon. The study started 20 May 2026 and is expected to finish 15 October 2027.
Contact: Rasha Hesham el dein mohammed, Bachelor.
Source: ClinicalTrials.gov, NCT07548918 (https://clinicaltrials.gov/study/NCT07548918).
Start date: May 20, 2026
Completion date: October 15, 2027
Organizer: Sohag University
Contact: Rasha Hesham el dein mohammed, Bachelor
Tel.: +201111199719
Email: rashahesham15@gmail.com
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FAQOther Questions
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