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Ruxolitinib Cream Combined With Corticosteroids for Progressive Non-Segmental Vitiligo: A Multicenter Real-World Study
Official title: Efficacy and Safety of Ruxolitinib Phosphate Cream Combined With Corticosteroids in Patients With Progressive Non-Segmental Vitiligo: A Multicenter Real-World Study
Status: Recruiting now
Description:
This study is a prospective, multicenter, real-world observational study to assess the clinical efficacy and safety of topical 1.5% Ruxolitinib phosphate cream used in combination with systemic corticosteroids in a real-world clinical setting. The study plans to observe patients aged 12 years and older with active, progressive non-segmental vitiligo involving the face. All treatments are prescribed based on standard routine clinical care and medical practice guidelines. Participants will apply Ruxolitinib cream twice daily to affected skin areas for up to 24 weeks alongside a standard corticosteroid regimen. The primary goal of the study is to evaluate how many patients achieve a 75% or greater improvement in their facial vitiligo patches after 12 weeks of combined treatment. Safety and side effects will also be closely monitored throughout the 24-week period.
What is being studied: drugs — 1.5% Ruxolitinib Phosphate Cream (Opzelura), Corticosteroid Therapy.
Who can take part: ages 12 Years, 300 participants planned.
Enrollment status: Open now. The study started 02 July 2026 and is expected to finish 31 December 2028.
Contact: ShanShan Li.
Source: ClinicalTrials.gov, NCT07673640 (https://clinicaltrials.gov/study/NCT07673640).
Start date: July 02, 2026
Completion date: December 31, 2028
Organizer: ShanShan Li
Contact: ShanShan Li
Tel.: +86 18201346463
Email: lishanshan@cms.net.cn
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