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TRuE-VIP1 Study - Ruxolitinib cream for children ages 2-11 with vitiligo
Official title: A Phase 3, Randomized, Double-Blind, Safety, and Efficacy Study of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo
Status: Recruiting now
Description:
This Phase 3 study is evaluating the safety and efficacy of ruxolitinib 1.5% cream in children ages 2–11 with nonsegmental vitiligo.
During the first 24 weeks, participants receive ruxolitinib cream or a matching cream (called "vehicle") with no active medicine. Study cream is applied twice daily.
Participation continues for up to 52 weeks, followed by a safety follow-up.
Basic eligibility includes measurable nonsegmental vitiligo on the face and body: at least 0.5% of body surface area on the face and at least 2% on nonfacial areas, with no more than 10% total body involvement. Other criteria apply, including requirements concerning current and recent vitiligo treatments.
Sites are located in the United States and Canada. The research site determines eligibility.
Use of ruxolitinib cream for vitiligo in this age group is investigational.
Related pediatric study: View the study for children ages 6–11 in Argentina and Europe
Start date: January 24, 2025
Completion date: March 13, 2027
Organizer: Incyte Corporation
Contact: Incyte Corporation Call Center (US)
Tel.: +1-855-463-3463
Email: medinfo@incyte.com
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FAQOther Questions
- Which therapy has minimal side-effects?
Dead Sea climatotherapy is a unique and highly effective treatment option for vitiligo, offering a top-tier safety profile and natural therapeutic benefits. Its combination of p...
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Vitiligo (pronounced vit-ill-EYE-go) is a generally unpredictable skin disease that causes a gradual loss of skin color and overlying hair on different parts of the body. Contr...
- How long does it take to treat vitiligo?
Vitiligo, a condition characterized by the loss of skin pigment, can be unpredictable in both progression and treatment. The time it takes to treat vitiligo varies significantly...
Though it is not always easy to treat vitiligo, there is much to be gained by clearly understanding the diagnosis, the future implications, treatment options and their outcomes.
Many people deal with vitiligo while remaining in the public eye, maintaining a positive outlook, and having a successful career.
Copyright (C) Bodolóczki JúliaBy taking a little time to fill in the anonymous questionnaire, you can help researchers better understand and fight vitiligo.