Dermatology Outpatient Clinic, Kasr al Ainy Teaching Hospital, Cairo University, Cairo, Egypt - 03 Mar `26The Value of Methotrexate in NCES for Stable Vitiligo

The Value of Methotrexate in NCES for Stable Vitiligo

Official title: The Value of Using Methotrexate Therapy Along With Non Cultured Epidermal Cell Suspension (NCES) in Stable Resistant Vitiligo: An Interventional Prospective Randomized Controlled Trial.

Status: Closed to new participants

Description:

The goal of this clinical trial is to learn if adding a six months course of Methotrexate would improve the results of non cultured epidermal suspension (NCES) in adult patients with acral and resistant vitiligo lesions over the elbows and knees. researchers will compare results of NCES in two groups one group will receive Methotrexate for 3 months prior to the procedure and 3 months after the procedure, while the other group will not receive the drug. Patients will receive PUVA hand \& feet 3 times/week for 3 months after NCES during this period they will be followed up monthly to evaluate repigmentation.

Phase: Phase 4.

What is being studied: procedure — Non cultured epidermal suspension.

Who can take part: ages 18 Years, 20 participants planned.

Enrollment status: the registry has not updated this study since its planned completion date, so its current status is unclear. The study started 03 March 2026 and was due to finish 01 September 2026.

Source: ClinicalTrials.gov, NCT07352293 (https://clinicaltrials.gov/study/NCT07352293).

Start date: March 03, 2026

Completion date: September 01, 2026

Organizer: Cairo University

Link: https://clinicaltrials.gov/study/NCT07352293

The registry does not list a contact for this study. Use the link above to reach the study record on ClinicalTrials.gov.

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