Aswan University Hospital, Aswān, Egypt (Recruiting) - 01 Jun `26Tyrosine or fluorouracil with laser treatment for vitiligo

Tyrosine or fluorouracil with laser treatment for vitiligo

Official title: Efficacy of Topical Tyrosine Versus Topical 5-Fluorouracil With Fractional Erbium YAG Laser in Focal Vitiligo: A Randomised Clinical Trial

Status: Recruiting now

Description:

Aswan University plans to enroll about 40 participants. Fluorouracil is applied after needling or laser treatment to encourage pigment cells to move into pale skin. Researchers hope the combination will improve repigmentation in stable vitiligo. Fluorouracil is sold under brands including Efudex for certain precancerous and superficial cancerous skin lesions; vitiligo would be a new use. Possible effects include redness, pain, peeling, sores, pigment changes, and infection. People ages 18 to 60 may qualify. The study is recruiting at one listed site in Egypt.

Start date: June 01, 2026

Completion date: June 10, 2027

Organizer: Aswan University

Contact: Yasmin Mahdy Mohamed Ahmed, MSC

Tel.: +20 112 660 744 8

Email: yasmin17041133@aswu.edu.eg

Link: https://clinicaltrials.gov/study/NCT07742982

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FAQOther Questions

  • What's better: laser or phototherapy?

    Laser therapy is actually a type of phototherapy. Both rely on light to trigger changes in the skin, but they work differently. Phototherapy usually means a narrow-band UV (NB-U...

  • Will it spread?

    Vitiligo is famously unpredictable, but it doesn't move at random. By looking at thousands of cases, researchers have identified specific patterns of how the condition behaves. ...

  • Can a gluten-free diet help with vitiligo?

    It's very unlikely. We have specifically looked into claims that gluten-free diet may ease symptoms of vitiligo, or completely reverse it, and found no firm scientific evidence ...