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Tyrosine or fluorouracil with laser treatment for vitiligo
Official title: Efficacy of Topical Tyrosine Versus Topical 5-Fluorouracil With Fractional Erbium YAG Laser in Focal Vitiligo: A Randomised Clinical Trial
Status: Recruiting now
Description:
Aswan University plans to enroll about 40 participants. Fluorouracil is applied after needling or laser treatment to encourage pigment cells to move into pale skin. Researchers hope the combination will improve repigmentation in stable vitiligo. Fluorouracil is sold under brands including Efudex for certain precancerous and superficial cancerous skin lesions; vitiligo would be a new use. Possible effects include redness, pain, peeling, sores, pigment changes, and infection. People ages 18 to 60 may qualify. The study is recruiting at one listed site in Egypt.
Start date: June 01, 2026
Completion date: June 10, 2027
Organizer: Aswan University
Contact: Yasmin Mahdy Mohamed Ahmed, MSC
Tel.: +20 112 660 744 8
Email: yasmin17041133@aswu.edu.eg
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FAQOther Questions
- What are the best predictors for therapy response in vitiligo?
A fair question. Also a slightly annoying one, because dermatology loves nuance and patients usually want something more like a weather forecast. Still, a few factors do show up...
- What's better: laser or phototherapy?
Laser therapy is actually a type of phototherapy. Both rely on light to trigger changes in the skin, but they work differently. Phototherapy usually means a narrow-band UV (NB-U...
- What causes vitiligo?
The exact cause is a complex puzzle, but we know the foundation: It is pre-wired in your genes. Think of your genetics as a loaded spring, just waiting for a specific "trigger" ...
Though it is not always easy to treat vitiligo, there is much to be gained by clearly understanding the diagnosis, the future implications, treatment options and their outcomes.
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