Department of Dermatology and Venerology, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin, China (Recruiting) - 04 Dec `24Upadacitinib after pigment-cell transplant for vitiligo

Upadacitinib after pigment-cell transplant for vitiligo

Official title: Efficacy of Upadacitinib After Autologous Non-cultured Epidermal Cell Suspension Transplantation in Vitiligo Participants -- a Pilot, Random, Observer Blinded, Comparative Study

Status: Recruiting now

Description:

Jilin University plans to enroll about 60 participants. Upadacitinib is an oral JAK inhibitor that reduces inflammatory immune signaling. Researchers hope it will slow melanocyte destruction and improve repigmentation, alone or after cell transplantation. Upadacitinib is sold as Rinvoq and is approved for atopic dermatitis and several other inflammatory conditions; vitiligo would be a new use. Possible effects include infections, acne, nausea, and headache; serious risks can include blood clots and major cardiovascular events. People ages 18 to 60 may qualify. The study is recruiting at one listed site in China.

Start date: December 04, 2024

Completion date: June 01, 2029

Organizer: Jilin University

Contact: Bing Han

Tel.: +86 159 4307 3198

Email: pfk_hanbing@jlu.edu.cn

Link: https://clinicaltrials.gov/study/NCT06454461

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FAQOther Questions

  • What are risks of oral and topical corticosteroids?

    Corticosteroid drugs (like hydrocortisone, and others) are often used for treating vitiligo. By mimicing the effects of hormones your body produces naturally in your adrenal gla...

  • Will it spread?

    Vitiligo is famously unpredictable, but it doesn't move at random. By looking at thousands of cases, researchers have identified specific patterns of how the condition behaves. ...

  • How long does it take to treat vitiligo?

    Vitiligo, a condition characterized by the loss of skin pigment, can be unpredictable in both progression and treatment. The time it takes to treat vitiligo varies significantly...