13 listed sites: United States (13) - 15 Nov `24TEV-53408 antibody treatment for nonsegmental vitiligo

TEV-53408 antibody treatment for nonsegmental vitiligo

Official title: A Phase 1b, Open-Label Trial to Assess Safety and Exploratory Efficacy of TEV-53408 in Participants With Vitiligo

Status: Closed to new participants

Description:

Teva Branded Pharmaceutical Products R&D LLC plans to enroll about 66 participants. The experimental antibody blocks IL-15, an immune signal that helps pigment-destroying T cells survive. Researchers hope it will reduce the immune attack on melanocytes and allow skin color to return. Possible risks include injection or infusion reactions, headache, and infections; longer-term risks are still being studied. People ages 18 to 75 may qualify. The study is underway but is no longer accepting new participants.

Start date: November 11, 2024

Completion date: January 31, 2029

Organizer: Teva Branded Pharmaceutical Products R&D LLC

Contact: Teva Medical Expert, MD

Link: https://clinicaltrials.gov/study/NCT06625177

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FAQOther Questions

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    Localized vitiligo, where the white patches are limited to one or a few areas of the body, can be managed with a few treatment approaches. The best therapy usually depends on th...

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    The exact cause is a complex puzzle, but we know the foundation: It is pre-wired in your genes. Think of your genetics as a loaded spring, just waiting for a specific "trigger" ...