5 listed sites: France (5) - 05 May `24Deucravacitinib for nonsegmental vitiligo

Deucravacitinib for nonsegmental vitiligo

Official title: Vitiligo Treatment by Targeting TYK2 Mediated Responses Prospective Multicentric Double Blind Interventional Study

Status: Closed to new participants

Description:

Centre Hospitalier Universitaire de Nice plans to enroll about 128 participants. Deucravacitinib blocks TYK2, an immune enzyme involved in inflammatory signaling. Researchers hope it will reduce the immune attack on melanocytes and improve skin color. Deucravacitinib is sold as Sotyktu and is approved for plaque psoriasis; vitiligo would be a new use. Possible effects include respiratory infections, headache, acne, and mouth sores. People ages 18 to 75 may qualify. The study is underway but is no longer accepting new participants.

Start date: May 05, 2024

Completion date: July 05, 2027

Organizer: Centre Hospitalier Universitaire de Nice

Contact: PASSERON Thierry, PhD

Link: https://clinicaltrials.gov/study/NCT06327321

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