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Povorcitinib tablets for nonsegmental vitiligo
Official title: A Phase 3, Randomized, Double-Blind, 52-Week, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib in Participants With Nonsegmental Vitiligo
Status: Closed to new participants
Description:
Incyte Corporation enrolled about 467 participants. The study drug is an experimental oral or topical immune-modulating medicine designed to reduce inflammatory signaling. Researchers hope it will slow melanocyte damage and help skin regain color. Possible effects may include headache, stomach upset, skin irritation, and infections; the full safety profile is still being studied. People age 18 and older may qualify. The study is underway but is no longer accepting new participants.
Start date: November 29, 2023
Completion date: February 24, 2027
Organizer: Incyte Corporation
Contact: Incyte Medical Monitor
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FAQOther Questions
- Which is better for judging vitiligo — Wood’s lamp or dermoscopy?
A recent study out of India compared the two head-to-head. Both tools correlated fairly well with clinical criteria, but dermoscopy had a slight edge: Wood’s lamp: sensitivity 7...
- Can chemicals cause vitiligo?
Certain chemicals can trigger vitiligo, leading to a condition known as chemical-induced vitiligo. While clinically and histologically indistinguishable from other types of viti...
- What are the best predictors for therapy response in vitiligo?
A fair question. Also a slightly annoying one, because dermatology loves nuance and patients usually want something more like a weather forecast. Still, a few factors do show up...
Though it is not always easy to treat vitiligo, there is much to be gained by clearly understanding the diagnosis, the future implications, treatment options and their outcomes.
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