Faculty of medicine, Al-Azhar University Assuit, Asyut, Asyut Governorate, 71511, Egypt - 30 Sep `26Fractional CO2 Laser vs Dermabrasion With 5-Fluorouracil for Acquired Leukoderma

Fractional CO2 Laser vs Dermabrasion With 5-Fluorouracil for Acquired Leukoderma

Official title: Fractional Co2 Laser vs Dermabrasion 5-Flurouracil Delivery in Acquired Leukoderma: A Comparative Study

Status: Opening soon

Description:

This randomized controlled prospective single-blinded comparative clinical study aims to compare the efficacy and safety of fractional carbon dioxide (CO2) laser therapy versus mechanical dermabrasion, both combined with topical 5-fluorouracil, in the treatment of acquired non-vitiligo leukoderma. The study will evaluate repigmentation, clinical improvement, patient satisfaction, and treatment-related adverse effects.

What is being studied: device — Fractional CO2 Laser; procedure — Dermabrasion; drug — 5-Fluorouracil.

Who can take part: ages 18 Years to 75 Years, 16 participants planned.

Enrollment status: Opening soon. The study started 26 August 2026 and is expected to finish 26 August 2027.

Contact: Walaa Ashraf Sayed.

Source: ClinicalTrials.gov, NCT07837908 (https://clinicaltrials.gov/study/NCT07837908).

Start date: August 26, 2026

Completion date: August 26, 2027

Organizer: Al-Azhar University

Contact: Walaa Ashraf Sayed

Tel.: MBBS

Email: walaaashraf464@yahoo.com

Link: https://clinicaltrials.gov/study/NCT07837908

Clinical Trial Alerts

Sign up and be the first to know about updates on this trial.

This request will be sent with the trial reference Fractional CO2 Laser vs Dermabrasion With 5-Fluorouracil for Acquired Leukoderma . By submitting you agree to our Privacy Policy.

FAQOther Questions

  • How can I cure vitiligo?

    Right now, there is no universal "cure," but we have entered a new era of treatment. Today, managing vitiligo isn’t just about "hiding" it; it’s about sophisticated science that...

  • What are the best predictors for therapy response in vitiligo?

    A fair question. Also a slightly annoying one, because dermatology loves nuance and patients usually want something more like a weather forecast. Still, a few factors do show up...

  • Vitiligo trials for kids: basics for the parents

    Pediatric vitiligo trials · The basics Two parallel studies are evaluating investigational use of ruxolitinib cream in young children — researchers are still finding out how wel...