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Ritlecitinib with or without UVB light therapy
Official title: Combination Approach With Ritlecitinib and nbUVB Compared to Ritlecitinib Alone for Treating Vitiligo Prospective Multicentric Evaluator Blinded Interventional Study
Status: Recruiting now
Description:
Centre Hospitalier Universitaire de Nice plans to enroll about 56 participants. Ritlecitinib is an oral immune-modulating drug that blocks JAK3 and TEC-family signaling. Researchers hope it will reduce the immune attack on melanocytes and support repigmentation. Ritlecitinib is sold as Litfulo and is approved for severe alopecia areata in people age 12 and older; vitiligo would be a new use. Possible effects include headache, diarrhea, acne, and infections. People age 18 and older may qualify. The study is recruiting at 5 listed sites in France.
Start date: March 12, 2026
Completion date: June 01, 2029
Organizer: Centre Hospitalier Universitaire de Nice
Contact: Thierry Passeron, PhD
Tel.: +33 492 036 488
Email: passeron.t@chu-nice.fr
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FAQOther Questions
- What are risks of oral and topical corticosteroids?
Corticosteroid drugs (like hydrocortisone, and others) are often used for treating vitiligo. By mimicing the effects of hormones your body produces naturally in your adrenal gla...
- Isn't it just a cosmetic disorder?
Contrary to popular belief, vitiligo is not merely a cosmetic issue but a complex autoimmune disorder that affects the body’s largest organ—along with other vital systems—and is...
- Does halo nevi affect vitiligo development?
Halo nevi (also known as Sutton's nevi) are characterized by a mole that's surrounded by a ring of depigmented or lighter skin. While both halo nevi and vitiligo involve the des...
Though it is not always easy to treat vitiligo, there is much to be gained by clearly understanding the diagnosis, the future implications, treatment options and their outcomes.
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