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Ruxolitinib cream for nonsegmental vitiligo
Official title: Topical Ruxolitinib for the Treatment of Immune-related Vitiligo-like Depigmentation: A Prospective, Multicentre Study of a Topical JAK-inhibitor
Status: Closed to new participants
Description:
University of Zurich plans to enroll about 34 participants. Ruxolitinib cream blocks JAK1 and JAK2 signals that help sustain the immune attack on pigment-producing cells. It is intended to calm inflammation and help affected skin regain color. Ruxolitinib cream is sold as Opzelura and is already approved in the United States for nonsegmental vitiligo in people age 12 and older and for atopic dermatitis. The study is testing a particular population or treatment approach. Possible effects include application-site acne, itching or redness, headache, and infections. People age 18 and older may qualify. The study is underway but is no longer accepting new participants.
Start date: July 25, 2024
Completion date: August 31, 2026
Organizer: University of Zurich
Contact: See contacts and locations in the ClinicalTrials.gov record
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