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Zasocitinib Tablets for Nonsegmental Vitiligo
Official title: A Phase 2, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Dose-Ranging Trial to Evaluate the Efficacy and Safety of Zasocitinib in Participants With Nonsegmental Vitiligo
Status: Recruiting now
Description:
Vitiligo is a long-term autoimmune condition that causes the skin to lose its color. The body's germ-fighting system (immune system) mistakenly attacks the skin cells (melanocytes) which produce the pigment that gives the skin color (melanin). This leads to the formation of patches of skin with less or no pigment (depigmentation). These patches can occur anywhere on the body. In the nonsegmental form of vitiligo, similar patches occur on both sides of the body (symmetrical patches). The main aim of this study is to learn how safe zasocitinib is, how well it works and how well it is tolerated by adults with nonsegmental vitiligo. The participants will receive the study treatment (either zasocitinib or placebo) for up to 1 year (52 weeks). The placebo looks like the zasocitinib capsule but does not have any medicine in it. Participants who receive placebo at the beginning will change to...
Phase: Phase 2.
What is being studied: Drug: Zasocitinib; Other: Placebo.
Who can take part: ages 18 Years to 75 Years, 200 participants planned.
Enrollment status: Open now. The study starts 03 November 2025 and expected to finish 09 November 2027.
Contact: Takeda Contact, +1-877-825-3327, medinfoUS@takeda.com.
Source: ClinicalTrials.gov, NCT07108283 (https://clinicaltrials.gov/study/NCT07108283).
Start date: November 03, 2025
Completion date: November 09, 2027
Organizer: Takeda
Contact: Takeda Contact, +1-877-825-3327
Tel.: +1-877-825-3327
Email: medinfoUS@takeda.com
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FAQOther Questions
- Can a gluten-free diet help with vitiligo?
It's very unlikely. We have specifically looked into claims that gluten-free diet may ease symptoms of vitiligo, or completely reverse it, and found no firm scientific evidence ...
- Isn't it just a cosmetic disorder?
Contrary to popular belief, vitiligo is not merely a cosmetic issue but a complex autoimmune disorder that affects the body’s largest organ—along with other vital systems—and is...
- What are rules for military service entry with vitiligo?
Military service · Patient guide How do military-service rules for vitiligo differ across countries? There is no global standard. Every country writes its own entry rules, and m...
Though it is not always easy to treat vitiligo, there is much to be gained by clearly understanding the diagnosis, the future implications, treatment options and their outcomes.
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