In a study published in the Journal Nature Genetics today, Prof. Richard Spritz, MD, Director of the Human Medical Genetics and Genomics Program at the University of Colorado, and a team of international researchers, - including VRF - announced new genetic links to vitiligo. Researchers conducted genome-wide association studies on 4,680 people with vitiligo and 39,586 control cases and found the genes that provide a framework for the genetic architecture and biological mechanisms of vitiligo. They also highlight relationships with other autoimmune diseases and melanoma.
By identifying new genes and specifics of gene regulations, the investigators can highlight and further investigate potential targets for treatment. A better understanding of the causes of vitiligo could also lead to breakthroughs in other conditions, such as: thyroid disease, pernicious anemia, rheumatoid arthritis, type 1 diabetes, Addison's disease and lupus. Read 'Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants'
- Will it spread?
Vitiligo activity may vary considerably from person to person. In a good number of patients the disease goes on for 3-4 years and then it settles down, with one or two stubborn...
- What tests should be done?
A well-trained dermatologist should be able to diagnose vitiligo and distinguish it from contact leukoderma or more than twenty other conditions with similar skin appearance bas...
- Pyrostegia venusta as a folk medicine for vitiligo?
Pyrostegia venusta is a neotropical evergreen vine widely spread in Brazil throughout fields, at the coast, edge of the woods and along roadsides (see photo below). Popularly kn...
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Though it is not always easy to treat vitiligo, there is much to be gained by clearly understanding the diagnosis, the future implications, treatment options and their outcomes.
Many people deal with vitiligo while remaining in the public eye, maintaining a positive outlook, and having a successful career.Copyright (C) Bodolóczki Júlia
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